Fig. 5

Quantitative analysis of dynamic blood flow changes. a Introduction of the selected area (circled by red) for VAD analysis, and three representative vessels from group A, B and C for diameter changes analysis. Group A: Vessels that did not get blocked or did not disappear during the long-term monitoring, but were from the core area. Group B: Vessels that got blocked and disappeared from the core. Group C: Vessels from the periphery. b VAD analysis and vessel diameter changed analysis, normalized to the normal state. Core area: inside the red circle in (a) peripheral area: outside the red circle in (a c and d) Comparison between the normal state and 10 days after stroke. Red lines: the same vessels which can be manually identified. Blue circle in (d) newly generated vessels that cannot be found in the same area in (c) Scale bars at bottom left, 200 μm